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The Cellular State Determines the Effect of Melatonin on the Survival of Mixed Cerebellar Cell Culture
The constitutive activation of nuclear factor-κB (NF-κB), a key transcription factor involved in neuroinflammation, is essential for the survival of neurons in situ and of cerebellar granule cells in culture. Melatonin is known to inhibit the activation of NF-κB and has a cytoprotective function. In...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153619/ https://www.ncbi.nlm.nih.gov/pubmed/25184316 http://dx.doi.org/10.1371/journal.pone.0106332 |