The Interferon-Induced Gene Ifi27l2a is Active in Lung Macrophages and Lymphocytes After Influenza A Infection but Deletion of Ifi27l2a in Mice Does Not Increase Susceptibility to Infection

Interferons represent one of the first and essential host defense mechanisms after infection, and the activation of the IFN-pathway results in the transcriptional activation of hundreds of interferon-stimulated genes. The alpha-inducible protein 27 like 2A (Ifi27l2a) gene (human synonym: ISG12) is s...

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Detalles Bibliográficos
Autores principales: Tantawy, Mohamed A., Hatesuer, Bastian, Wilk, Esther, Dengler, Leonie, Kasnitz, Nadine, Weiß, Siegfried, Schughart, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153650/
https://www.ncbi.nlm.nih.gov/pubmed/25184786
http://dx.doi.org/10.1371/journal.pone.0106392

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