Heat Hyperalgesia and Mechanical Hypersensitivity Induced by Calcitonin Gene-Related Peptide in a Mouse Model of Neurofibromatosis

This study examined whether mice with a deficiency of neurofibromin, a Ras GTPase activating protein, exhibit a nociceptive phenotype and probed a possible contribution by calcitonin gene-related peptide. In the absence of inflammation, Nf1(+/−) mice (B6.129S6 Nf1<tm1Fcr>/J) and wild type litt...

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Detalles Bibliográficos
Autores principales: White, Stephanie, Marquez de Prado, Blanca, Russo, Andrew F., Hammond, Donna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153688/
https://www.ncbi.nlm.nih.gov/pubmed/25184332
http://dx.doi.org/10.1371/journal.pone.0106767

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