Combination of hepatocyte specific delivery and transformation dependent expression of shRNA inducing transcriptional gene silencing of c-Myc promoter in hepatocellular carcinoma cells

BACKGROUND: A specific targeting modality for hepatocellular carcinoma (HCC) could ideally encompass a liver cell specific delivery system of a transcriptional unit that is active only in neoplastic cells. Sendai virosomes, derived from Sendai viral envelopes, home to hepatocytes based on the liver...

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Detalles Bibliográficos
Autores principales: Zakaria, Mohammad Khalid, Khan, Imran, Mani, Prashant, Chattopadhyay, Parthaprasad, Sarkar, Debi P, Sinha, Subrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153911/
https://www.ncbi.nlm.nih.gov/pubmed/25108398
http://dx.doi.org/10.1186/1471-2407-14-582

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