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Potential viral pathogenic mechanism in human type 1 diabetes

In type 1 diabetes, as a result of as yet unknown triggering events, auto-aggressive CD8(+) T cells, together with a significant number of other inflammatory cells, including CD8(+) T lymphocytes with unknown specificity, infiltrate the pancreas, leading to insulitis and destruction of the insulin-p...

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Detalles Bibliográficos
Autores principales: Schneider, Darius A., von Herrath, Matthias G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153966/
https://www.ncbi.nlm.nih.gov/pubmed/25073445
http://dx.doi.org/10.1007/s00125-014-3340-7