A Novel Suspension Formulation Enhances Intestinal Absorption of Macromolecules Via Transient and Reversible Transport Mechanisms

PURPOSE: Medium chain fatty acid salts promote absorption by increasing paracellular permeability of the intestinal epithelium. Novel oily suspension (OS) formulation disperses a powder containing sodium caprylate and macromolecules such as octreotide or fluorescent dextran (FD). Formulation safety,...

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Detalles Bibliográficos
Autores principales: Tuvia, Shmuel, Pelled, Dori, Marom, Karen, Salama, Paul, Levin-Arama, Maya, Karmeli, Irina, Idelson, Gregory H., Landau, Isaac, Mamluk, Roni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153969/
https://www.ncbi.nlm.nih.gov/pubmed/24558008
http://dx.doi.org/10.1007/s11095-014-1303-9

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