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A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis

Non-alcoholic fatty liver disease (NAFLD) represents the most common liver disease in Western countries and often progresses to non-alcoholic steatohepatitis (NASH) leading ultimately to liver fibrosis and liver cancer. The occurrence of hepatocyte cell death—so far characterized as hepatocyte apopt...

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Detalles Bibliográficos
Autores principales: Gautheron, Jérémie, Vucur, Mihael, Reisinger, Florian, Cardenas, David Vargas, Roderburg, Christoph, Koppe, Christiane, Kreggenwinkel, Karina, Schneider, Anne Theres, Bartneck, Matthias, Neumann, Ulf Peter, Canbay, Ali, Reeves, Helen Louise, Luedde, Mark, Tacke, Frank, Trautwein, Christian, Heikenwalder, Mathias, Luedde, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154133/
https://www.ncbi.nlm.nih.gov/pubmed/24963148
http://dx.doi.org/10.15252/emmm.201403856