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A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis
Non-alcoholic fatty liver disease (NAFLD) represents the most common liver disease in Western countries and often progresses to non-alcoholic steatohepatitis (NASH) leading ultimately to liver fibrosis and liver cancer. The occurrence of hepatocyte cell death—so far characterized as hepatocyte apopt...
Autores principales: | Gautheron, Jérémie, Vucur, Mihael, Reisinger, Florian, Cardenas, David Vargas, Roderburg, Christoph, Koppe, Christiane, Kreggenwinkel, Karina, Schneider, Anne Theres, Bartneck, Matthias, Neumann, Ulf Peter, Canbay, Ali, Reeves, Helen Louise, Luedde, Mark, Tacke, Frank, Trautwein, Christian, Heikenwalder, Mathias, Luedde, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154133/ https://www.ncbi.nlm.nih.gov/pubmed/24963148 http://dx.doi.org/10.15252/emmm.201403856 |
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