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A fast Monte Carlo code for proton transport in radiation therapy based on MCNPX

An important requirement for proton therapy is a software for dose calculation. Monte Carlo is the most accurate method for dose calculation, but it is very slow. In this work, a method is developed to improve the speed of dose calculation. The method is based on pre-generated tracks for particle tr...

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Detalles Bibliográficos
Autores principales: Jabbari, Keyvan, Seuntjens, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154183/
https://www.ncbi.nlm.nih.gov/pubmed/25190994
http://dx.doi.org/10.4103/0971-6203.139004
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author Jabbari, Keyvan
Seuntjens, Jan
author_facet Jabbari, Keyvan
Seuntjens, Jan
author_sort Jabbari, Keyvan
collection PubMed
description An important requirement for proton therapy is a software for dose calculation. Monte Carlo is the most accurate method for dose calculation, but it is very slow. In this work, a method is developed to improve the speed of dose calculation. The method is based on pre-generated tracks for particle transport. The MCNPX code has been used for generation of tracks. A set of data including the track of the particle was produced in each particular material (water, air, lung tissue, bone, and soft tissue). This code can transport protons in wide range of energies (up to 200 MeV for proton). The validity of the fast Monte Carlo (MC) code is evaluated with data MCNPX as a reference code. While analytical pencil beam algorithm transport shows great errors (up to 10%) near small high density heterogeneities, there was less than 2% deviation of MCNPX results in our dose calculation and isodose distribution. In terms of speed, the code runs 200 times faster than MCNPX. In the Fast MC code which is developed in this work, it takes the system less than 2 minutes to calculate dose for 10(6) particles in an Intel Core 2 Duo 2.66 GHZ desktop computer.
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spelling pubmed-41541832014-09-04 A fast Monte Carlo code for proton transport in radiation therapy based on MCNPX Jabbari, Keyvan Seuntjens, Jan J Med Phys Original Article An important requirement for proton therapy is a software for dose calculation. Monte Carlo is the most accurate method for dose calculation, but it is very slow. In this work, a method is developed to improve the speed of dose calculation. The method is based on pre-generated tracks for particle transport. The MCNPX code has been used for generation of tracks. A set of data including the track of the particle was produced in each particular material (water, air, lung tissue, bone, and soft tissue). This code can transport protons in wide range of energies (up to 200 MeV for proton). The validity of the fast Monte Carlo (MC) code is evaluated with data MCNPX as a reference code. While analytical pencil beam algorithm transport shows great errors (up to 10%) near small high density heterogeneities, there was less than 2% deviation of MCNPX results in our dose calculation and isodose distribution. In terms of speed, the code runs 200 times faster than MCNPX. In the Fast MC code which is developed in this work, it takes the system less than 2 minutes to calculate dose for 10(6) particles in an Intel Core 2 Duo 2.66 GHZ desktop computer. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4154183/ /pubmed/25190994 http://dx.doi.org/10.4103/0971-6203.139004 Text en Copyright: © Journal of Medical Physics http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Jabbari, Keyvan
Seuntjens, Jan
A fast Monte Carlo code for proton transport in radiation therapy based on MCNPX
title A fast Monte Carlo code for proton transport in radiation therapy based on MCNPX
title_full A fast Monte Carlo code for proton transport in radiation therapy based on MCNPX
title_fullStr A fast Monte Carlo code for proton transport in radiation therapy based on MCNPX
title_full_unstemmed A fast Monte Carlo code for proton transport in radiation therapy based on MCNPX
title_short A fast Monte Carlo code for proton transport in radiation therapy based on MCNPX
title_sort fast monte carlo code for proton transport in radiation therapy based on mcnpx
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154183/
https://www.ncbi.nlm.nih.gov/pubmed/25190994
http://dx.doi.org/10.4103/0971-6203.139004
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