Therapeutic Advancements in Multiple Myeloma

Multiple myeloma survival has significantly improved in the latest years due to a broad spectrum of novel agents available for treatment. The introduction of thalidomide, bortezomib, and lenalidomide together with autologous stem-cell transplantation has considerably increased complete remission rat...

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Autores principales: Gozzetti, Alessandro, Candi, Veronica, Papini, Giulia, Bocchia, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154387/
https://www.ncbi.nlm.nih.gov/pubmed/25237651
http://dx.doi.org/10.3389/fonc.2014.00241
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author Gozzetti, Alessandro
Candi, Veronica
Papini, Giulia
Bocchia, Monica
author_facet Gozzetti, Alessandro
Candi, Veronica
Papini, Giulia
Bocchia, Monica
author_sort Gozzetti, Alessandro
collection PubMed
description Multiple myeloma survival has significantly improved in the latest years due to a broad spectrum of novel agents available for treatment. The introduction of thalidomide, bortezomib, and lenalidomide together with autologous stem-cell transplantation has considerably increased complete remission rate and progression-free survival resulting ultimately in prolonged survival in myeloma patients. Moreover, novel strategies of treatment such as consolidation and maintenance are being used to further implement responses. Finally, a number of new drugs such as carfilzomib and pomalidomide are already in clinical practice, making the future of myeloma patients brighter.
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spelling pubmed-41543872014-09-18 Therapeutic Advancements in Multiple Myeloma Gozzetti, Alessandro Candi, Veronica Papini, Giulia Bocchia, Monica Front Oncol Oncology Multiple myeloma survival has significantly improved in the latest years due to a broad spectrum of novel agents available for treatment. The introduction of thalidomide, bortezomib, and lenalidomide together with autologous stem-cell transplantation has considerably increased complete remission rate and progression-free survival resulting ultimately in prolonged survival in myeloma patients. Moreover, novel strategies of treatment such as consolidation and maintenance are being used to further implement responses. Finally, a number of new drugs such as carfilzomib and pomalidomide are already in clinical practice, making the future of myeloma patients brighter. Frontiers Media S.A. 2014-09-04 /pmc/articles/PMC4154387/ /pubmed/25237651 http://dx.doi.org/10.3389/fonc.2014.00241 Text en Copyright © 2014 Gozzetti, Candi, Papini and Bocchia. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Gozzetti, Alessandro
Candi, Veronica
Papini, Giulia
Bocchia, Monica
Therapeutic Advancements in Multiple Myeloma
title Therapeutic Advancements in Multiple Myeloma
title_full Therapeutic Advancements in Multiple Myeloma
title_fullStr Therapeutic Advancements in Multiple Myeloma
title_full_unstemmed Therapeutic Advancements in Multiple Myeloma
title_short Therapeutic Advancements in Multiple Myeloma
title_sort therapeutic advancements in multiple myeloma
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154387/
https://www.ncbi.nlm.nih.gov/pubmed/25237651
http://dx.doi.org/10.3389/fonc.2014.00241
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