Resolution of inflammation: targeting GPCRs that interact with lipids and peptides()

There is a growing appreciation of the important role of resolution mediators in the successful termination of the inflammatory response. Here, we discuss the potential importance of the lipid and peptide proresolving mediators, in particular the resolvins and chemerin-derived peptides, which mediat...

Descripción completa

Detalles Bibliográficos
Autores principales: Cash, Jenna L., Norling, Lucy V., Perretti, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd. ;, Distributed by Virgin Mailing and Distribution 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154450/
https://www.ncbi.nlm.nih.gov/pubmed/24993159
http://dx.doi.org/10.1016/j.drudis.2014.06.023
_version_ 1782333423907504128
author Cash, Jenna L.
Norling, Lucy V.
Perretti, Mauro
author_facet Cash, Jenna L.
Norling, Lucy V.
Perretti, Mauro
author_sort Cash, Jenna L.
collection PubMed
description There is a growing appreciation of the important role of resolution mediators in the successful termination of the inflammatory response. Here, we discuss the potential importance of the lipid and peptide proresolving mediators, in particular the resolvins and chemerin-derived peptides, which mediate their effects through specific G protein-coupled receptors (GPCRs).
format Online
Article
Text
id pubmed-4154450
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Elsevier Science Ltd. ;, Distributed by Virgin Mailing and Distribution
record_format MEDLINE/PubMed
spelling pubmed-41544502014-09-06 Resolution of inflammation: targeting GPCRs that interact with lipids and peptides() Cash, Jenna L. Norling, Lucy V. Perretti, Mauro Drug Discov Today Review There is a growing appreciation of the important role of resolution mediators in the successful termination of the inflammatory response. Here, we discuss the potential importance of the lipid and peptide proresolving mediators, in particular the resolvins and chemerin-derived peptides, which mediate their effects through specific G protein-coupled receptors (GPCRs). Elsevier Science Ltd. ;, Distributed by Virgin Mailing and Distribution 2014-08 /pmc/articles/PMC4154450/ /pubmed/24993159 http://dx.doi.org/10.1016/j.drudis.2014.06.023 Text en © 2014 The Authors https://creativecommons.org/licenses/by/3.0/This work is licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by/3.0/) .
spellingShingle Review
Cash, Jenna L.
Norling, Lucy V.
Perretti, Mauro
Resolution of inflammation: targeting GPCRs that interact with lipids and peptides()
title Resolution of inflammation: targeting GPCRs that interact with lipids and peptides()
title_full Resolution of inflammation: targeting GPCRs that interact with lipids and peptides()
title_fullStr Resolution of inflammation: targeting GPCRs that interact with lipids and peptides()
title_full_unstemmed Resolution of inflammation: targeting GPCRs that interact with lipids and peptides()
title_short Resolution of inflammation: targeting GPCRs that interact with lipids and peptides()
title_sort resolution of inflammation: targeting gpcrs that interact with lipids and peptides()
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154450/
https://www.ncbi.nlm.nih.gov/pubmed/24993159
http://dx.doi.org/10.1016/j.drudis.2014.06.023
work_keys_str_mv AT cashjennal resolutionofinflammationtargetinggpcrsthatinteractwithlipidsandpeptides
AT norlinglucyv resolutionofinflammationtargetinggpcrsthatinteractwithlipidsandpeptides
AT perrettimauro resolutionofinflammationtargetinggpcrsthatinteractwithlipidsandpeptides

Ejemplares similares