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Differential contribution of TRPM4 and TRPM5 nonselective cation channels to the slow afterdepolarization in mouse prefrontal cortex neurons
In certain neurons from different brain regions, a brief burst of action potentials can activate a slow afterdepolarization (sADP) in the presence of muscarinic acetylcholine receptor agonists. The sADP, if suprathreshold, can contribute to persistent non-accommodating firing in some of these neuron...
Autores principales: | Lei, Ya-Ting, Thuault, Sebastien J., Launay, Pierre, Margolskee, Robert F., Kandel, Eric R., Siegelbaum, Steven A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154465/ https://www.ncbi.nlm.nih.gov/pubmed/25237295 http://dx.doi.org/10.3389/fncel.2014.00267 |
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