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Recombinant Modified Vaccinia Virus Ankara Expressing Glycoprotein E2 of Chikungunya Virus Protects AG129 Mice against Lethal Challenge

Chikungunya virus (CHIKV) infection is characterized by rash, acute high fever, chills, headache, nausea, photophobia, vomiting, and severe polyarthralgia. There is evidence that arthralgia can persist for years and result in long-term discomfort. Neurologic disease with fatal outcome has been docum...

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Detalles Bibliográficos
Autores principales: van den Doel, Petra, Volz, Asisa, Roose, Jouke M., Sewbalaksing, Varsha D., Pijlman, Gorben P., van Middelkoop, Ingeborg, Duiverman, Vincent, van de Wetering, Eva, Sutter, Gerd, Osterhaus, Albert D. M. E., Martina, Byron E. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154657/
https://www.ncbi.nlm.nih.gov/pubmed/25188230
http://dx.doi.org/10.1371/journal.pntd.0003101