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Striatal Astrocytes Act as a Reservoir for L-DOPA

L-DOPA is therapeutically efficacious in patients with Parkinson’s disease (PD), although dopamine (DA) neurons are severely degenerated. Since cortical astrocytes express neutral amino acid transporter (LAT) and DA transporter (DAT), the uptake and metabolism of L-DOPA and DA in striatal astrocytes...

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Detalles Bibliográficos
Autores principales:	Asanuma, Masato, Miyazaki, Ikuko, Murakami, Shinki, Diaz-Corrales, Francisco J., Ogawa, Norio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154692/ https://www.ncbi.nlm.nih.gov/pubmed/25188235 http://dx.doi.org/10.1371/journal.pone.0106362

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