Overexpression of the Novel MATE Fluoroquinolone Efflux Pump FepA in Listeria monocytogenes Is Driven by Inactivation of Its Local Repressor FepR

Whereas fluoroquinolone resistance mainly results from target modifications in gram-positive bacteria, it is primarily due to active efflux in Listeria monocytogenes. The aim of this study was to dissect a novel molecular mechanism of fluoroquinolone resistance in this important human pathogen. Isog...

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Detalles Bibliográficos
Autores principales: Guérin, François, Galimand, Marc, Tuambilangana, Fabrice, Courvalin, Patrice, Cattoir, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154695/
https://www.ncbi.nlm.nih.gov/pubmed/25188450
http://dx.doi.org/10.1371/journal.pone.0106340

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