Histone H3 Lysine 36 Methyltransferase Whsc1 Promotes the Association of Runx2 and p300 in the Activation of Bone-Related Genes

The orchestration of histone modifiers is required to establish the epigenomic status that regulates gene expression during development. Whsc1 (Wolf-Hirschhorn Syndrome candidate 1), a histone H3 lysine 36 (H3K36) trimethyltransferase, is one of the major genes associated with Wolf-Hirshhorn syndrom...

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Detalles Bibliográficos
Autores principales: Lee, Yu Fei, Nimura, Keisuke, Lo, Wan Ning, Saga, Kotaro, Kaneda, Yasufumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154728/
https://www.ncbi.nlm.nih.gov/pubmed/25188294
http://dx.doi.org/10.1371/journal.pone.0106661

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