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Distinct Dictation of Japanese Encephalitis Virus-Induced Neuroinflammation and Lethality via Triggering TLR3 and TLR4 Signal Pathways

Japanese encephalitis (JE) is major emerging neurologic disease caused by JE virus. To date, the impact of TLR molecules on JE progression has not been addressed. Here, we determined whether each TLR modulates JE, using several TLR-deficient mouse strains (TLR2, TLR3, TLR4, TLR7, TLR9). Surprisingly...

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Detalles Bibliográficos
Autores principales:	Han, Young Woo, Choi, Jin Young, Uyangaa, Erdenebelig, Kim, Seong Bum, Kim, Jin Hyoung, Kim, Bum Seok, Kim, Koanhoi, Eo, Seong Kug
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154777/ https://www.ncbi.nlm.nih.gov/pubmed/25188232 http://dx.doi.org/10.1371/journal.ppat.1004319

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