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The Use of a Stably Expressed FRET Biosensor for Determining the Potency of Cancer Drugs
Many cancer drugs are intended to kill cancer cells by inducing apoptosis. However, the potency assays used for measuring the bioactivity of these products are generally cell viability assays which do not distinguish between cell death and growth inhibition. Here we describe a cell-based fluorescenc...
Autores principales: | Bozza, William P., Di, Xu, Takeda, Kazuyo, Rivera Rosado, Leslie A., Pariser, Sarah, Zhang, Baolin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154796/ https://www.ncbi.nlm.nih.gov/pubmed/25188024 http://dx.doi.org/10.1371/journal.pone.0107010 |
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