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The Use of a Stably Expressed FRET Biosensor for Determining the Potency of Cancer Drugs

Many cancer drugs are intended to kill cancer cells by inducing apoptosis. However, the potency assays used for measuring the bioactivity of these products are generally cell viability assays which do not distinguish between cell death and growth inhibition. Here we describe a cell-based fluorescenc...

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Detalles Bibliográficos
Autores principales: Bozza, William P., Di, Xu, Takeda, Kazuyo, Rivera Rosado, Leslie A., Pariser, Sarah, Zhang, Baolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154796/
https://www.ncbi.nlm.nih.gov/pubmed/25188024
http://dx.doi.org/10.1371/journal.pone.0107010

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