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Epidemiology and clinical impact of major comorbidities in patients with COPD

Comorbidities are frequent in chronic obstructive pulmonary disease (COPD) and significantly impact on patients’ quality of life, exacerbation frequency, and survival. There is increasing evidence that certain diseases occur in greater frequency amongst patients with COPD than in the general populat...

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Autores principales: Smith, Miranda Caroline, Wrobel, Jeremy P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154888/
https://www.ncbi.nlm.nih.gov/pubmed/25210449
http://dx.doi.org/10.2147/COPD.S49621
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author Smith, Miranda Caroline
Wrobel, Jeremy P
author_facet Smith, Miranda Caroline
Wrobel, Jeremy P
author_sort Smith, Miranda Caroline
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description Comorbidities are frequent in chronic obstructive pulmonary disease (COPD) and significantly impact on patients’ quality of life, exacerbation frequency, and survival. There is increasing evidence that certain diseases occur in greater frequency amongst patients with COPD than in the general population, and that these comorbidities significantly impact on patient outcomes. Although the mechanisms are yet to be defined, many comorbidities likely result from the chronic inflammatory state that is present in COPD. Common problems in the clinical management of COPD include recognizing new comorbidities, determining the impact of comorbidities on patient symptoms, the concurrent treatment of COPD and comorbidities, and accurate prognostication. The majority of comorbidities in COPD should be treated according to usual practice, and specific COPD management is infrequently altered by the presence of comorbidities. Unfortunately, comorbidities are often under-recognized and under-treated. This review focuses on the epidemiology of ten major comorbidities in patients with COPD. Further, we emphasize the clinical impact upon prognosis and management considerations. This review will highlight the importance of comorbidity identification and management in the practice of caring for patients with COPD.
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spelling pubmed-41548882014-09-10 Epidemiology and clinical impact of major comorbidities in patients with COPD Smith, Miranda Caroline Wrobel, Jeremy P Int J Chron Obstruct Pulmon Dis Review Comorbidities are frequent in chronic obstructive pulmonary disease (COPD) and significantly impact on patients’ quality of life, exacerbation frequency, and survival. There is increasing evidence that certain diseases occur in greater frequency amongst patients with COPD than in the general population, and that these comorbidities significantly impact on patient outcomes. Although the mechanisms are yet to be defined, many comorbidities likely result from the chronic inflammatory state that is present in COPD. Common problems in the clinical management of COPD include recognizing new comorbidities, determining the impact of comorbidities on patient symptoms, the concurrent treatment of COPD and comorbidities, and accurate prognostication. The majority of comorbidities in COPD should be treated according to usual practice, and specific COPD management is infrequently altered by the presence of comorbidities. Unfortunately, comorbidities are often under-recognized and under-treated. This review focuses on the epidemiology of ten major comorbidities in patients with COPD. Further, we emphasize the clinical impact upon prognosis and management considerations. This review will highlight the importance of comorbidity identification and management in the practice of caring for patients with COPD. Dove Medical Press 2014-08-27 /pmc/articles/PMC4154888/ /pubmed/25210449 http://dx.doi.org/10.2147/COPD.S49621 Text en © 2014 Smith and Wrobel. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Smith, Miranda Caroline
Wrobel, Jeremy P
Epidemiology and clinical impact of major comorbidities in patients with COPD
title Epidemiology and clinical impact of major comorbidities in patients with COPD
title_full Epidemiology and clinical impact of major comorbidities in patients with COPD
title_fullStr Epidemiology and clinical impact of major comorbidities in patients with COPD
title_full_unstemmed Epidemiology and clinical impact of major comorbidities in patients with COPD
title_short Epidemiology and clinical impact of major comorbidities in patients with COPD
title_sort epidemiology and clinical impact of major comorbidities in patients with copd
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154888/
https://www.ncbi.nlm.nih.gov/pubmed/25210449
http://dx.doi.org/10.2147/COPD.S49621
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