Sphingosine kinase 1 mediates head & neck squamous cell carcinoma invasion through sphingosine 1-phosphate receptor 1

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is characterized by aggressive loco-regional invasion. Sphingosine kinase1 (SphK1), an enzyme in sphingolipid metabolism, is emerging as a key player in HNSCC pathology. The observation that SphK1 is overexpressed in all HNSCC stages and is a...

Descripción completa

Detalles Bibliográficos
Autores principales: Tamashiro, Paulette M, Furuya, Hideki, Shimizu, Yoshiko, Kawamori, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155094/
https://www.ncbi.nlm.nih.gov/pubmed/25197261
http://dx.doi.org/10.1186/s12935-014-0076-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155094/
https://www.ncbi.nlm.nih.gov/pubmed/25197261
http://dx.doi.org/10.1186/s12935-014-0076-x

Ejemplares similares