Antibiotic prescription and cost patterns in a general intensive care unit

Antibiotic prescription habits, cost pattern, and the prospective intervention in an Intensive Care Unit were analyzed. METHODS: Data on antibiotic utilization and costs were collected prospectively from individual electronic charts from August 2003 to January 2004, and retrospectively from August t...

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Detalles Bibliográficos
Autores principales: Krivoy, Norberto, El-Ahal, Wissam Abed, Bar-Lavie, Yaron, Haddad, Salim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centro de Investigaciones y Publicaciones Farmaceuticas 2007
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155153/
https://www.ncbi.nlm.nih.gov/pubmed/25214920
Descripción
Sumario:Antibiotic prescription habits, cost pattern, and the prospective intervention in an Intensive Care Unit were analyzed. METHODS: Data on antibiotic utilization and costs were collected prospectively from individual electronic charts from August 2003 to January 2004, and retrospectively from August to December 2002. RESULTS: A total of 180 and 107 patients were surveyed in 2002 and 2003. In 2002, Piperacillin-Tazobactam (13.8%) and Imipenem/Cilastin (11.2%) were the most prescribed medications; while, in 2003, Vancomycin (12.6%) and Imipenem/Cilastin (11.3%) were prescribed, respectively. Total defined daily dose (DDD) and Drug Utilization 90% (DU90%) index for 2002 and 2003 were 2031.15 and 2325.90 DDDs (p>0.1) and 1777.57 and 2079.61 DU90%, respectively (p>0.1). The Median Total Cost /100 admission days (CI 95%) were NIS13,310 (11,110;18,420) and NIS13,860 (6,710;18,020) (p=0.66), respectively. CONCLUSIONS: Interventional programs should focus on promoting infectious control with rational antibiotic prescription aimed at minimizing the future emergence of bacterial resistance and futile expenses.

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