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Intestinal Protease-Activated Receptor-2 and Fecal Serine Protease Activity are Increased in Canine Inflammatory Bowel Disease and May Contribute to Intestinal Cytokine Expression

Serine proteases elicit cellular responses via protease-activated receptor-2 (PAR-2) which is known to regulate inflammation and the immune response. Although the gastrointestinal tract is exposed to large amounts of proteolytic enzymes, the role of PAR-2 in canine inflammatory bowel disease (IBD) r...

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Detalles Bibliográficos
Autores principales:	MAEDA, Shingo, OHNO, Koichi, UCHIDA, Kazuyuki, IGARASHI, Hirotaka, GOTO-KOSHINO, Yuko, FUJINO, Yasuhito, TSUJIMOTO, Hajime
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Japanese Society of Veterinary Science 2014
Materias:	Internal Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155192/ https://www.ncbi.nlm.nih.gov/pubmed/24829081 http://dx.doi.org/10.1292/jvms.14-0060

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