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Repression of Hepatic Cytochrome P450 2D Expression in Mice during Babesia microti Infection

To examine the effect of Babesia infection on the level of the drug-metabolizing enzyme hepatic cytochrome P450 (CYP) 2D, we intraperitoneally inoculated Babesia microti into male ICR mice. CYP2D protein and CYP2D9 mRNA were significantly decreased at 12 days after infection with B. microti. The act...

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Detalles Bibliográficos
Autores principales: SHIMAMOTO, Yoshinori, WATANABE, Kensuke, IKADAI, Hiromi, OKAMURA, Masashi, ISHIZUKA, Mayumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155197/
https://www.ncbi.nlm.nih.gov/pubmed/24784440
http://dx.doi.org/10.1292/jvms.14-0109

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