A Study on Borna Disease Virus Infection in Domestic Cats in Japan

Borna disease virus (BDV) infection causes neurological disease in cats. Here, we report BDV infection in 199 hospitalized domestic cats in the Tokyo area. BDV infection was evaluated by detection of plasma antibodies against BDV-p24 or -p40. BDV-specific antibodies were detected in 54 cats (27.1%)....

Descripción completa

Detalles Bibliográficos
Autores principales: SOMEYA, Azusa, FUKUSHIMA, Ryoko, YOSHIDA, Michiko, TANAHASHI, Yasuyuki, PRAPEUK, Tangmunkhong, IIZUKA, Reiko, HIRAMI, Hiroshi, MATSUDA, Atsushi, TAKAHASHI, Shunichi, KURITA, Goro, KIMURA, Takashi, SEO, Misuzu, FUNABA, Masayuki, NISHINO, Yoshii
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2014
Materias:
Virology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155199/
https://www.ncbi.nlm.nih.gov/pubmed/24805904
http://dx.doi.org/10.1292/jvms.13-0349
Descripción
Sumario:Borna disease virus (BDV) infection causes neurological disease in cats. Here, we report BDV infection in 199 hospitalized domestic cats in the Tokyo area. BDV infection was evaluated by detection of plasma antibodies against BDV-p24 or -p40. BDV-specific antibodies were detected in 54 cats (27.1%). Interestingly, the percentage of seropositive cats was not significantly different among the three clinical groups, i.e., healthy (29.8%), neurologically asymptomatic disease (22.2%) and neurological disease (33.3%). The specific antibodies were present even in cats aged below one year. The seropositive ratio was constant, irrespective of age and sampling season. The present study suggests that additional factors are required for onset of Borna disease in naturally infected cats and that BDV is transmitted through vertical routes in cats.

Ejemplares similares