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Clostridium difficile has a single sortase, SrtB, that can be inhibited by small-molecule inhibitors
BACKGROUND: Bacterial sortases are transpeptidases that covalently anchor surface proteins to the peptidoglycan of the Gram-positive cell wall. Sortase protein anchoring is mediated by a conserved cell wall sorting signal on the anchored protein, comprising of a C-terminal recognition sequence conta...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155245/ https://www.ncbi.nlm.nih.gov/pubmed/25183427 http://dx.doi.org/10.1186/s12866-014-0219-1 |