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Generation and characterization of influenza A viruses with altered polymerase fidelity

Genetic diversity of influenza A viruses (IAV) acquired through the error-prone RNA-dependent RNA polymerase (RdRP) or genetic reassortment enables perpetuation of IAV in humans through epidemics or pandemics. Here, to assess the biological significance of genetic diversity acquired through RdRP, we...

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Detalles Bibliográficos
Autores principales:	Cheung, Peter PH, Watson, Simon J., Choy, Ka-Tim, Sia, Sin Fun, Wong, Diana DY, Poon, Leo LM, Kellam, Paul, Guan, Yi, Peiris, JS Malik, Yen, Hui-Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155405/ https://www.ncbi.nlm.nih.gov/pubmed/25183443 http://dx.doi.org/10.1038/ncomms5794

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