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Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in rats
BACKGROUND: Minocycline, a semi-synthetic tetracycline antibiotic, is an effective neuroprotective agent in animal models of cerebral ischemia when given in high doses intraperitoneally. The aim of this study was to determine if minocycline was effective at reducing infarct size in a Temporary Middl...
Autores principales: | Xu, Lin, Fagan, Susan C, Waller, Jennifer L, Edwards, David, Borlongan, Cesar V, Zheng, Jianqing, Hill, William D, Feuerstein, Giora, Hess, David C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC415551/ https://www.ncbi.nlm.nih.gov/pubmed/15109399 http://dx.doi.org/10.1186/1471-2377-4-7 |
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