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Reversibility of Retinal Microvascular Changes in Severe Falciparum Malaria
Malarial retinopathy allows detailed study of central nervous system vascular pathology in living patients with severe malaria. An adult with cerebral malaria is described who had prominent retinal whitening with corresponding retinal microvascular obstruction, vessel dilatation, increased vascular...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Tropical Medicine and Hygiene
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155549/ https://www.ncbi.nlm.nih.gov/pubmed/24935949 http://dx.doi.org/10.4269/ajtmh.14-0116 |
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author | Maude, Richard J. Kingston, Hugh W. F. Joshi, Sonia Mohanty, Sanjib Mishra, Saroj K. White, Nicholas J. Dondorp, Arjen M. |
author_facet | Maude, Richard J. Kingston, Hugh W. F. Joshi, Sonia Mohanty, Sanjib Mishra, Saroj K. White, Nicholas J. Dondorp, Arjen M. |
author_sort | Maude, Richard J. |
collection | PubMed |
description | Malarial retinopathy allows detailed study of central nervous system vascular pathology in living patients with severe malaria. An adult with cerebral malaria is described who had prominent retinal whitening with corresponding retinal microvascular obstruction, vessel dilatation, increased vascular tortuosity, and blood retinal barrier leakage with decreased visual acuity, all of which resolved on recovery. Additional study of these features and their potential role in elucidating the pathogenesis of cerebral malaria is warranted. |
format | Online Article Text |
id | pubmed-4155549 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | The American Society of Tropical Medicine and Hygiene |
record_format | MEDLINE/PubMed |
spelling | pubmed-41555492014-09-09 Reversibility of Retinal Microvascular Changes in Severe Falciparum Malaria Maude, Richard J. Kingston, Hugh W. F. Joshi, Sonia Mohanty, Sanjib Mishra, Saroj K. White, Nicholas J. Dondorp, Arjen M. Am J Trop Med Hyg Articles Malarial retinopathy allows detailed study of central nervous system vascular pathology in living patients with severe malaria. An adult with cerebral malaria is described who had prominent retinal whitening with corresponding retinal microvascular obstruction, vessel dilatation, increased vascular tortuosity, and blood retinal barrier leakage with decreased visual acuity, all of which resolved on recovery. Additional study of these features and their potential role in elucidating the pathogenesis of cerebral malaria is warranted. The American Society of Tropical Medicine and Hygiene 2014-09-03 /pmc/articles/PMC4155549/ /pubmed/24935949 http://dx.doi.org/10.4269/ajtmh.14-0116 Text en ©The American Society of Tropical Medicine and Hygiene This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Articles Maude, Richard J. Kingston, Hugh W. F. Joshi, Sonia Mohanty, Sanjib Mishra, Saroj K. White, Nicholas J. Dondorp, Arjen M. Reversibility of Retinal Microvascular Changes in Severe Falciparum Malaria |
title | Reversibility of Retinal Microvascular Changes in Severe Falciparum Malaria |
title_full | Reversibility of Retinal Microvascular Changes in Severe Falciparum Malaria |
title_fullStr | Reversibility of Retinal Microvascular Changes in Severe Falciparum Malaria |
title_full_unstemmed | Reversibility of Retinal Microvascular Changes in Severe Falciparum Malaria |
title_short | Reversibility of Retinal Microvascular Changes in Severe Falciparum Malaria |
title_sort | reversibility of retinal microvascular changes in severe falciparum malaria |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155549/ https://www.ncbi.nlm.nih.gov/pubmed/24935949 http://dx.doi.org/10.4269/ajtmh.14-0116 |
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