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Statistical monitoring of weak spots for improvement of normalization and ratio estimates in microarrays
BACKGROUND: Several aspects of microarray data analysis are dependent on identification of genes expressed at or near the limits of detection. For example, regression-based normalization methods rely on the premise that most genes in compared samples are expressed at similar levels and therefore req...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC415561/ https://www.ncbi.nlm.nih.gov/pubmed/15128432 http://dx.doi.org/10.1186/1471-2105-5-53 |