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RNAi-mediated knockdown of E2F2 inhibits tumorigenicity of human glioblastoma cells

In a previous genome-wide expression profiling study, we identified E2F2 as a hyperexpressed gene in stem-like cells of distinct glioblastoma multiforme (GBM) specimens. Since the encoded E2F2 transcription factor has been implicated in both tumor suppression and tumor development, we conducted a fu...

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Detalles Bibliográficos
Autores principales: NAKAHATA, ADRIANA M., SUZUKI, DANIELA E., RODINI, CAROLINA O., FIUZA, MAYARA L., OKAMOTO, OSWALDO K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156183/
https://www.ncbi.nlm.nih.gov/pubmed/25202354
http://dx.doi.org/10.3892/ol.2014.2369