Cargando…

Expression of DNA topoisomerase II-α: Clinical significance in laryngeal carcinoma

DNA topoisomerase II-α (Topo II-α) is essential for numerous cell processes, including DNA replication, transcription, recombination, and chromosome separation and condensation. Altered Topo II-α expression may lead to carcinogenesis and cancer progression. The aim of the present study was to invest...

Descripción completa

Detalles Bibliográficos
Autores principales:	FENG, YAN, ZHANG, HAILI, GAO, WEI, WEN, SHUXIN, HUANGFU, HUI, SUN, RUIFANG, BAI, WEI, WANG, BINQUAN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156233/ https://www.ncbi.nlm.nih.gov/pubmed/25202370 http://dx.doi.org/10.3892/ol.2014.2367

Ejemplares similares

Fascin-1, Ezrin and Paxillin Contribute to the Malignant Progression and Are Predictors of Clinical Prognosis in Laryngeal Squamous Cell Carcinoma
por: Gao, Wei, et al.
Publicado: (2012)

Hsa-miR-301a-3p Acts as an Oncogene in Laryngeal Squamous Cell Carcinoma via Target Regulation of Smad4
por: Lu, Yan, et al.
Publicado: (2015)

Association between UGT1A1 Polymorphism and Risk of Laryngeal Squamous Cell Carcinoma
por: Huangfu, Hui, et al.
Publicado: (2016)

Alterations of bacterial communities of vocal cord mucous membrane increases the risk for glottic laryngeal squamous cell carcinoma
por: Dong, Zhen, et al.
Publicado: (2021)

Metastasis-associated gene 1 promotes invasion and migration potential of laryngeal squamous cell carcinoma cells
por: ZHANG, HAILI, et al.
Publicado: (2014)

Serum Exosomal miR-941 as a promising Oncogenic Biomarker for Laryngeal Squamous Cell Carcinoma
por: Zhao, Qinli, et al.
Publicado: (2020)

The Significance of Topoisomerase II Alpha in Invasive Breast Carcinoma
por: Arthi, M, et al.
Publicado: (2021)

Natural Products as Topoisomerase II Poisons: Effects of Thymoquinone on DNA Cleavage Mediated by Human Topoisomerase IIα
por: Ashley, Rachel E., et al.
Publicado: (2014)

Effect of HPV Infection on the Occurrence and Development of Laryngeal Cancer: A Review
por: Yang, Dongli, et al.
Publicado: (2019)

Identification and characterization of CD133(+)CD44(+) cancer stem cells from human laryngeal squamous cell carcinoma cell lines
por: Wang, Jue, et al.
Publicado: (2017)

DNA topoisomerase IIα and Ki67 are prognostic factors in patients with hepatocellular carcinoma
por: Cao, Yi, et al.
Publicado: (2017)

Analysis of gene expression profiling variations induced by hsa-miR-145-5p-overexpression in laryngeal squamous cell carcinoma cell line Tu-177
por: Ding, Yongxia, et al.
Publicado: (2017)

MicroRNA-204-5p inhibits invasion and metastasis of laryngeal squamous cell carcinoma by suppressing forkhead box C1
por: Gao, Wei, et al.
Publicado: (2017)

Dynamics of human DNA topoisomerases IIα and IIβ in living cells
por: Christensen, Morten O., et al.
Publicado: (2002)

DNA topoisomerase IIα and -β expression in human ovarian cancer
por: Withoff, S, et al.
Publicado: (1999)

PIASy-dependent SUMOylation regulates DNA topoisomerase IIα activity
por: Ryu, Hyunju, et al.
Publicado: (2010)

miR-424-5p Promotes Proliferation, Migration and Invasion of Laryngeal Squamous Cell Carcinoma
por: Li, Yujun, et al.
Publicado: (2019)

Examining the Impact of Antimicrobial Fluoroquinolones on Human DNA Topoisomerase IIα and IIβ
por: Fief, Cole A., et al.
Publicado: (2019)

A novel microRNA panel exhibited significant potential in evaluating the progression of laryngeal squamous cell carcinoma
por: Zhang, Linshi, et al.
Publicado: (2023)

Topoisomerase IIα in Chromosome Instability and Personalized Cancer Therapy
por: Chen, Tao, et al.
Publicado: (2014)

DNA topoisomerase IIα expression and the response toprimary chemotherapy in breast cancer
por: MacGrogan, G, et al.
Publicado: (2003)

Effects of DNA topoisomerase IIα splice variants on acquired drug resistance
por: Elton, Terry S., et al.
Publicado: (2020)

Roles of the C-terminal domains of topoisomerase IIα and topoisomerase IIβ in regulation of the decatenation checkpoint
por: Kozuki, Toshiyuki, et al.
Publicado: (2017)

The Impact of the C-Terminal Domain on the Interaction of Human DNA Topoisomerase II α and β with DNA
por: Gilroy, Kathryn L., et al.
Publicado: (2011)

mSWI/SNF (BAF) Complexes Facilitate Decatentation of DNA by Topoisomerase IIα
por: Dykhuizen, Emily C., et al.
Publicado: (2013)

Substituted 4,5′-Bithiazoles as Catalytic Inhibitors of Human DNA Topoisomerase IIα
por: Bergant Loboda, Kaja, et al.
Publicado: (2020)

Catalytic Mechanism of ATP Hydrolysis in the ATPase Domain of Human DNA Topoisomerase IIα
por: Ogrizek, Mitja, et al.
Publicado: (2022)

Developmental regulation of Drosophila DNA topoisomerase II
Publicado: (1991)

The Roles of DNA Topoisomerase IIβ in Transcription
por: Madabhushi, Ram
Publicado: (2018)

Targeting DNA Topoisomerase II in Antifungal Chemotherapy
por: Kondaka, Kavya, et al.
Publicado: (2022)

Prognostic significance of artemin and GFRα1 expression in laryngeal squamous cell carcinoma
por: GAO, CHAOBING, et al.
Publicado: (2014)

Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II
por: Xu, Huanli, et al.
Publicado: (2016)

Resolution of human ribosomal DNA occurs in anaphase, dependent on tankyrase 1, condensin II, and topoisomerase IIα
por: Daniloski, Zharko, et al.
Publicado: (2019)

Human topoisomerase IIα uses a two-metal-ion mechanism for DNA cleavage
por: Deweese, Joseph E., et al.
Publicado: (2008)

Catalytic Core of Human Topoisomerase IIα: Insights into Enzyme–DNA Interactions and Drug Mechanism
por: Lindsey, R. Hunter, et al.
Publicado: (2014)

QSAR and docking studies on xanthone derivatives for anticancer activity targeting DNA topoisomerase IIα
por: Alam, Sarfaraz, et al.
Publicado: (2014)

Exploration of the Role of the C-Terminal Domain of Human DNA Topoisomerase IIα in Catalytic Activity
por: Dougherty, Ashley C., et al.
Publicado: (2021)

Dynophore-Based Approach in Virtual Screening: A Case of Human DNA Topoisomerase IIα
por: Janežič, Matej, et al.
Publicado: (2021)

Phenotypic Discovery of Thiocarbohydrazone with Anticancer Properties and Catalytic Inhibition of Human DNA Topoisomerase IIα
por: Cvijetić, Ilija N., et al.
Publicado: (2023)

Enhanced etoposide sensitivity following adenovirus-mediated human topoisomerase II α gene transfer is independent of topoisomerase II β
por: Zhou, Z, et al.
Publicado: (2001)

Cannot write session to /tmp/vufind_sessions/sess_pkqajru3rfv6n60pi0i6p76tjo