Thiol-Activated gem-Dithiols: A New Class of Controllable Hydrogen Sulfide Donors

[Image: see text] A class of novel thiol-activated H(2)S donors has been developed on the basis of the gem-dithiol template. These donors release H(2)S in the presence of cysteine or GSH in aqueous solutions as well as in cellular environments.

Detalles Bibliográficos
Autores principales: Zhao, Yu, Kang, Jianming, Park, Chung-Min, Bagdon, Powell E., Peng, Bo, Xian, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156246/
https://www.ncbi.nlm.nih.gov/pubmed/25141097
http://dx.doi.org/10.1021/ol502088m
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author Zhao, Yu
Kang, Jianming
Park, Chung-Min
Bagdon, Powell E.
Peng, Bo
Xian, Ming
author_facet Zhao, Yu
Kang, Jianming
Park, Chung-Min
Bagdon, Powell E.
Peng, Bo
Xian, Ming
author_sort Zhao, Yu
collection PubMed
description [Image: see text] A class of novel thiol-activated H(2)S donors has been developed on the basis of the gem-dithiol template. These donors release H(2)S in the presence of cysteine or GSH in aqueous solutions as well as in cellular environments.
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spelling pubmed-41562462015-08-20 Thiol-Activated gem-Dithiols: A New Class of Controllable Hydrogen Sulfide Donors Zhao, Yu Kang, Jianming Park, Chung-Min Bagdon, Powell E. Peng, Bo Xian, Ming Org Lett [Image: see text] A class of novel thiol-activated H(2)S donors has been developed on the basis of the gem-dithiol template. These donors release H(2)S in the presence of cysteine or GSH in aqueous solutions as well as in cellular environments. American Chemical Society 2014-08-20 2014-09-05 /pmc/articles/PMC4156246/ /pubmed/25141097 http://dx.doi.org/10.1021/ol502088m Text en Copyright © 2014 American Chemical Society Terms of Use (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html)
spellingShingle Zhao, Yu
Kang, Jianming
Park, Chung-Min
Bagdon, Powell E.
Peng, Bo
Xian, Ming
Thiol-Activated gem-Dithiols: A New Class of Controllable Hydrogen Sulfide Donors
title Thiol-Activated gem-Dithiols: A New Class of Controllable Hydrogen Sulfide Donors
title_full Thiol-Activated gem-Dithiols: A New Class of Controllable Hydrogen Sulfide Donors
title_fullStr Thiol-Activated gem-Dithiols: A New Class of Controllable Hydrogen Sulfide Donors
title_full_unstemmed Thiol-Activated gem-Dithiols: A New Class of Controllable Hydrogen Sulfide Donors
title_short Thiol-Activated gem-Dithiols: A New Class of Controllable Hydrogen Sulfide Donors
title_sort thiol-activated gem-dithiols: a new class of controllable hydrogen sulfide donors
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156246/
https://www.ncbi.nlm.nih.gov/pubmed/25141097
http://dx.doi.org/10.1021/ol502088m
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AT bagdonpowelle thiolactivatedgemdithiolsanewclassofcontrollablehydrogensulfidedonors
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