Catalytic Enantioselective Protoboration of Disubstituted Allenes. Access to Alkenylboron Compounds in High Enantiomeric Purity

[Image: see text] Proto-boryl additions to 1,1-disubstituted allenes in the presence of 1.0–5.0 mol % of chiral NHC–Cu complexes, B(2)(pin)(2), and t-BuOH proceed to afford alkenyl–B(pin) products in up to 98% yield, >98:2 site selectivity, and 98:2 er. The enantiomerically enriched alkenylboron...

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Detalles Bibliográficos
Autores principales: Jang, Hwanjong, Jung, Byunghyuck, Hoveyda, Amir H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156252/
https://www.ncbi.nlm.nih.gov/pubmed/25153792
http://dx.doi.org/10.1021/ol5022417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156252/
https://www.ncbi.nlm.nih.gov/pubmed/25153792
http://dx.doi.org/10.1021/ol5022417

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