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Comparing SILAC- and Stable Isotope Dimethyl-Labeling Approaches for Quantitative Proteomics

[Image: see text] Stable isotope labeling is widely used to encode and quantify proteins in mass-spectrometry-based proteomics. We compared metabolic labeling with stable isotope labeling by amino acids in cell culture (SILAC) and chemical labeling by stable isotope dimethyl labeling and find that t...

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Detalles Bibliográficos
Autores principales: Lau, Ho-Tak, Suh, Hyong Won, Golkowski, Martin, Ong, Shao-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156256/
https://www.ncbi.nlm.nih.gov/pubmed/25077673
http://dx.doi.org/10.1021/pr500630a