Novel HIV-1 MiRNAs Stimulate TNFα Release in Human Macrophages via TLR8 Signaling Pathway

PURPOSE: To determine whether HIV-1 produces microRNAs and elucidate whether these miRNAs can induce inflammatory response in macrophages (independent of the conventional miRNA function in RNA interference) leading to chronic immune activation. METHODS: Using sensitive quantitative Real Time RT-PCR...

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Detalles Bibliográficos
Autores principales: Bernard, Mark A., Zhao, Hui, Yue, Simon C., Anandaiah, Asha, Koziel, Henry, Tachado, Souvenir D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156304/
https://www.ncbi.nlm.nih.gov/pubmed/25191859
http://dx.doi.org/10.1371/journal.pone.0106006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156304/
https://www.ncbi.nlm.nih.gov/pubmed/25191859
http://dx.doi.org/10.1371/journal.pone.0106006

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