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Comparative Analysis of Evolutionarily Conserved Motifs of Epidermal Growth Factor Receptor 2 (HER2) Predicts Novel Potential Therapeutic Epitopes

Overexpression of human epidermal growth factor receptor 2 (HER2) is associated with tumor aggressiveness and poor prognosis in breast cancer. With the availability of therapeutic antibodies against HER2, great strides have been made in the clinical management of HER2 overexpressing breast cancer. H...

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Detalles Bibliográficos
Autores principales:	Deng, Xiaohong, Zheng, Xuxu, Yang, Huanming, Moreira, José Manuel Afonso, Brünner, Nils, Christensen, Henrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156330/ https://www.ncbi.nlm.nih.gov/pubmed/25192037 http://dx.doi.org/10.1371/journal.pone.0106448

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