Cargando…

Clinical Significance of the CCR5delta32 Allele in Hepatitis C

BACKGROUND: The CCR5 receptor, expressed on Th1 cells, may influence clinical outcomes of HCV infection. We explored a possible link between a CCR5 32-base deletion (CCR5delta32), resulting in the expression of a non-functioning receptor, and clinical outcomes of HCV infection. METHODS: CCR5 and HCV...

Descripción completa

Detalles Bibliográficos
Autores principales:	Morard, Isabelle, Clément, Sophie, Calmy, Alexandra, Mangia, Alessandra, Cerny, Andrea, De Gottardi, Andrea, Gorgievski, Meri, Heim, Markus, Malinverni, Raffaele, Moradpour, Darius, Müllhaupt, Beat, Semela, David, Pascarella, Stéphanie, Bochud, Pierre-Yves, Negro, Franco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156365/ https://www.ncbi.nlm.nih.gov/pubmed/25191700 http://dx.doi.org/10.1371/journal.pone.0106424

Ejemplares similares

Genetic Analyses Reveal a Role for Vitamin D Insufficiency in HCV-Associated Hepatocellular Carcinoma Development
por: Lange, Christian M., et al.
Publicado: (2013)

IL28B expression depends on a novel TT/-G polymorphism which improves HCV clearance prediction
por: Bibert, Stéphanie, et al.
Publicado: (2013)

All-Cause Mortality and Causes of Death in the Swiss Hepatitis C Cohort Study (SCCS)
por: Roelens, Maroussia, et al.
Publicado: (2020)

Impact of geographic origin on access to therapy and therapy outcomes in the Swiss Hepatitis C Cohort Study
por: Brezzi, Matteo, et al.
Publicado: (2019)

Prevalence of CCR5delta32 in Northeastern Iran
por: Tajbakhsh, Amir, et al.
Publicado: (2019)

Distribution of the CCR5delta32 allele (gene variant CCR5) in Rondônia, Western Amazonian region, Brazil
por: de Farias, Josileide Duarte, et al.
Publicado: (2012)

Characteristics of Foreign-Born Persons in the Swiss Hepatitis C Cohort Study: Implications for Screening Recommendations
por: Bertisch, Barbara, et al.
Publicado: (2016)

Distribution of the mutated delta 32 allele of CCR5 co-receptor gene in Iranian population
por: Rahimi, Hamzeh, et al.
Publicado: (2014)

HEK293T Cells Are Heterozygous for CCR5 Delta 32 Mutation
por: Qi, Chunxia, et al.
Publicado: (2016)

Modeling the Health and Economic Burden of Hepatitis C Virus in Switzerland
por: Müllhaupt, Beat, et al.
Publicado: (2015)

The global distribution of CCR5 delta 32 polymorphism: role in HIV-1 protection
por: Gupta, Anuroopa, et al.
Publicado: (2012)

Coregulation of HIV-1 dependency factors in individuals heterozygous to the CCR5-delta32 deletion
por: Hütter, Gero, et al.
Publicado: (2013)

Progress toward implementing the Swiss Hepatitis Strategy: Is HCV elimination possible by 2030?
por: Müllhaupt, Beat, et al.
Publicado: (2018)

Could FIV zoonosis responsible of the breakdown of the pathocenosis which has reduced the European CCR5-Delta32 allele frequencies?
por: Faure, Eric
Publicado: (2008)

The effect of the CCR5-delta32 deletion on global gene expression considering immune response and inflammation
por: Hütter, Gero, et al.
Publicado: (2011)

The CCR5-Delta32 Genetic Polymorphism and HIV-1 Infection Susceptibility: a Meta-analysis
por: Ni, Jun, et al.
Publicado: (2018)

Prevalence of CCR5 Delta 32 Genetic Variant in the Turkmen Population of Golestan Province, Northeast of Iran
por: Norasi, Elmira, et al.
Publicado: (2023)

A Genetic Validation Study Reveals a Role of Vitamin D Metabolism in the Response to Interferon-Alfa-Based Therapy of Chronic Hepatitis C
por: Lange, Christian M., et al.
Publicado: (2012)

A prospective, multicenter, post-marketing observational study to measure the quality of life of HCV genotype 1 infected, treatment naïve patients suffering from fatigue and receiving 3D regimen: The HEMATITE study
por: Semmo, Nasser, et al.
Publicado: (2020)

The Geographic Spread of the CCR5 Δ32 HIV-Resistance Allele
por: Novembre, John, et al.
Publicado: (2005)

The Case for Selection at CCR5-Δ32
por: Sabeti, Pardis C, et al.
Publicado: (2005)

Lack of association between the chemokine receptor 5 polymorphism CCR5delta32 in rheumatoid arthritis and juvenile idiopathic arthritis
por: Lindner, Ewald, et al.
Publicado: (2007)

HCV disease burden and population segments in Switzerland
por: Bihl, Florian, et al.
Publicado: (2021)

COVID-19 prevalence and mortality is associated with the allele frequency of CCR5-Δ32
por: Saadat, Mostafa
Publicado: (2021)

Partial protective effect of CCR5-Delta 32 heterozygosity in a cohort of heterosexual Italian HIV-1 exposed uninfected individuals
por: Trecarichi, Enrico M, et al.
Publicado: (2006)

Evaluating the Association between CCR5delta32 Polymorphism (rs333) and the Risk of Breast Cancer in a Cohort of Iranian Population
por: TAJBAKHSH, Amir, et al.
Publicado: (2021)

Distribution of CCR5-Delta32, CCR5 promoter 59029 A/G, CCR2-64I and SDF1-3’A genetic polymorphisms in HIV-1 infected and uninfected patients in the West Region of Cameroon
por: Nkenfou, Céline Nguefeu, et al.
Publicado: (2013)

The frequency of CCR5 promoter polymorphisms and CCR5 Δ 32 mutation in Iranian populations
por: Zare-Bidaki, Mohammad, et al.
Publicado: (2015)

CCR5del32 genotype in human enteroviral cardiomyopathy leads to spontaneous virus clearance and improved outcome compared to wildtype CCR5
por: Lassner, Dirk, et al.
Publicado: (2018)

Ccr2-64i and Ccr5 Δ32 Polymorphisms in Patients with Late-Onset Alzheimer’s disease; A Study from Iran (Ccr2-64i And Ccr5 Δ32 Polymorphisms in Alzheimer’s disease)
por: Khorram Khorshid, Hamid Reza, et al.
Publicado: (2012)

Rapid detection of respiratory picornaviruses in nasopharyngeal aspirates by immunofluorescence assay
por: Barbani, Maria Teresa, et al.
Publicado: (2009)

CCR2-64I and CCR5Δ32 Polymorphisms in Korean Patients with Myasthenia Gravis
por: Kim, Hyun Sook, et al.
Publicado: (2007)

Association between the CCR5Δ32 polymorphism and preeclampsia
por: Paula Telini, Bianca de, et al.
Publicado: (2014)

CCR5-Δ32 is deleterious in the homozygous state in humans
por: Wei, Xinzhu, et al.
Publicado: (2019)

The CCR5Δ32 allele is not a major predisposing factor for severe H1N1pdm09 infection
por: Sironi, Manuela, et al.
Publicado: (2014)

Beyond HIV infection: Neglected and varied impacts of CCR5 and CCR5Δ32 on viral diseases
por: Ellwanger, Joel Henrique, et al.
Publicado: (2020)

Low prevalence of CCR5-Δ32, CCR2-64I and SDF1-3′A alleles in the Baiga and Gond tribes of Central India
por: Bharti, Deepak, et al.
Publicado: (2015)

CCR5Δ32 Genotypes in a German HIV-1 Seroconverter Cohort and Report of HIV-1 Infection in a CCR5Δ32 Homozygous Individual
por: Oh, Djin-Ye, et al.
Publicado: (2008)

Detection of CCR5Δ32 Mutant Alleles in Heterogeneous Cell Mixtures Using Droplet Digital PCR
por: Sorokina, Alyona, et al.
Publicado: (2022)

Effects of the Chemokine Receptor 5 (CCR5)-Delta32 Mutation on Hepatitis C Virus-Specific Immune Responses and Liver Tissue Pathology in HCV Infected Patients
por: Yilmaz, Abdulkerim, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_h5n7bp0j766fdjoatioemrr9ci