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Role of Vitamin D(3) in Modulation of ΔNp63α Expression during UVB Induced Tumor Formation in SKH-1 Mice
ΔNp63α, a proto-oncogene, is up-regulated in non-melanoma skin cancers and directly regulates the expression of both Vitamin D receptor (VDR) and phosphatase and tensin homologue deleted on chromosome ten (PTEN). Since ΔNp63α has been shown to inhibit cell invasion via regulation of VDR, we wanted t...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156396/ https://www.ncbi.nlm.nih.gov/pubmed/25191969 http://dx.doi.org/10.1371/journal.pone.0107052 |