IL-12 is required for mTOR regulation of memory CTLs during viral infection

The induction of functional memory CTLs is a major goal of vaccination against intracellular pathogens. IL-12 is critical for the generation of memory CTLs, and inhibition of mTOR by rapamycin can effectively enhance the memory CTL response. Yet, the role of IL-12 in mTOR’s regulation of memory CTL...

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Detalles Bibliográficos
Autores principales: Garcia, Karla, Sun, Zhifeng, Mattson, Elliot, Li, Lei, Smyth, Kendra, Xiao, Zhengguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156562/
https://www.ncbi.nlm.nih.gov/pubmed/24898389
http://dx.doi.org/10.1038/gene.2014.33

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156562/
https://www.ncbi.nlm.nih.gov/pubmed/24898389
http://dx.doi.org/10.1038/gene.2014.33

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