Usefulness of a Darwinian System in a Biotechnological Application: Evolution of Optical Window Fluorescent Protein Variants under Selective Pressure

With rare exceptions, natural evolution is an extremely slow process. One particularly striking exception in the case of protein evolution is in the natural production of antibodies. Developing B cells activate and diversify their immunoglobulin (Ig) genes by recombination, gene conversion (GC) and...

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Detalles Bibliográficos
Autores principales: Schoetz, Ulrike, Deliolanis, Nikolaos C., Ng, David, Pauli, Jutta, Resch-Genger, Ute, Kühn, Enrico, Heuer, Steffen, Beisker, Wolfgang, Köster, Reinhard W., Zitzelsberger, Horst, Caldwell, Randolph B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156574/
https://www.ncbi.nlm.nih.gov/pubmed/25192257
http://dx.doi.org/10.1371/journal.pone.0107069

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