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Two distinct Do-Not-Resuscitate protocols leaving less to the imagination: an observational study using propensity score matching

BACKGROUND: Do-Not-Resuscitate (DNR) patients tend to receive less medical care after the order is written. To provide a clearer approach, the Ohio Department of Health adopted the Do-Not-Resuscitate law in 1998, indicating two distinct protocols of DNR orders that allow DNR patients to choose the m...

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Autores principales: Chen, Yen-Yuan, Gordon, Nahida H, Connors, Alfred F, Garland, Allan, Chang, Shan-Chwen, Youngner, Stuart J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156651/
https://www.ncbi.nlm.nih.gov/pubmed/25175307
http://dx.doi.org/10.1186/s12916-014-0146-x
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author Chen, Yen-Yuan
Gordon, Nahida H
Connors, Alfred F
Garland, Allan
Chang, Shan-Chwen
Youngner, Stuart J
author_facet Chen, Yen-Yuan
Gordon, Nahida H
Connors, Alfred F
Garland, Allan
Chang, Shan-Chwen
Youngner, Stuart J
author_sort Chen, Yen-Yuan
collection PubMed
description BACKGROUND: Do-Not-Resuscitate (DNR) patients tend to receive less medical care after the order is written. To provide a clearer approach, the Ohio Department of Health adopted the Do-Not-Resuscitate law in 1998, indicating two distinct protocols of DNR orders that allow DNR patients to choose the medical care: DNR Comfort Care (DNRCC), implying DNRCC patients receive only comfort care after the order is written; and DNR Comfort Care-Arrest (DNRCC-Arrest), implying that DNRCC-Arrest patients are eligible to receive aggressive interventions until cardiac or respiratory arrest. The aim of this study was to examine the medical care provided to patients with these two distinct protocols of DNR orders. METHODS: Data were collected from August 2002 to December 2005 at a medical intensive care unit in a university-affiliated teaching hospital. In total, 188 DNRCC-Arrest patients, 88 DNRCC patients, and 2,051 non-DNR patients were included. Propensity score matching using multivariate logistic regression was used to balance the confounding variables between the 188 DNRCC-Arrest and 2,051 non-DNR patients, and between the 88 DNRCC and 2,051 non-DNR patients. The daily cost of intensive care unit (ICU) stay, the daily cost of hospital stay, the daily discretionary cost of ICU stay, six aggressive interventions, and three comfort care measures were used to indicate the medical care patients received. The association of each continuous variable and categorical variable with having a DNR order written was analyzed using Student’s t-test and the χ(2) test, respectively. The six aggressive interventions and three comfort care measures performed before and after the order was initiated were compared using McNemar’s test. RESULTS: DNRCC patients received significantly fewer aggressive interventions and more comfort care after the order was initiated. By contrast, for DNRCC-Arrest patients, the six aggressive interventions provided were not significantly decreased, but the three comfort care measures were significantly increased after the order was initiated. In addition, the three medical costs were not significantly different between DNRCC and non-DNR patients, or between DNRCC-Arrest and non-DNR patients. CONCLUSIONS: When medical care provided to DNR patients is clearly indicated, healthcare professionals will provide the medical care determined by patient/surrogate decision-makers and healthcare professionals, rather than blindly decreasing medical care. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12916-014-0146-x) contains supplementary material, which is available to authorized users.
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spelling pubmed-41566512014-09-07 Two distinct Do-Not-Resuscitate protocols leaving less to the imagination: an observational study using propensity score matching Chen, Yen-Yuan Gordon, Nahida H Connors, Alfred F Garland, Allan Chang, Shan-Chwen Youngner, Stuart J BMC Med Research Article BACKGROUND: Do-Not-Resuscitate (DNR) patients tend to receive less medical care after the order is written. To provide a clearer approach, the Ohio Department of Health adopted the Do-Not-Resuscitate law in 1998, indicating two distinct protocols of DNR orders that allow DNR patients to choose the medical care: DNR Comfort Care (DNRCC), implying DNRCC patients receive only comfort care after the order is written; and DNR Comfort Care-Arrest (DNRCC-Arrest), implying that DNRCC-Arrest patients are eligible to receive aggressive interventions until cardiac or respiratory arrest. The aim of this study was to examine the medical care provided to patients with these two distinct protocols of DNR orders. METHODS: Data were collected from August 2002 to December 2005 at a medical intensive care unit in a university-affiliated teaching hospital. In total, 188 DNRCC-Arrest patients, 88 DNRCC patients, and 2,051 non-DNR patients were included. Propensity score matching using multivariate logistic regression was used to balance the confounding variables between the 188 DNRCC-Arrest and 2,051 non-DNR patients, and between the 88 DNRCC and 2,051 non-DNR patients. The daily cost of intensive care unit (ICU) stay, the daily cost of hospital stay, the daily discretionary cost of ICU stay, six aggressive interventions, and three comfort care measures were used to indicate the medical care patients received. The association of each continuous variable and categorical variable with having a DNR order written was analyzed using Student’s t-test and the χ(2) test, respectively. The six aggressive interventions and three comfort care measures performed before and after the order was initiated were compared using McNemar’s test. RESULTS: DNRCC patients received significantly fewer aggressive interventions and more comfort care after the order was initiated. By contrast, for DNRCC-Arrest patients, the six aggressive interventions provided were not significantly decreased, but the three comfort care measures were significantly increased after the order was initiated. In addition, the three medical costs were not significantly different between DNRCC and non-DNR patients, or between DNRCC-Arrest and non-DNR patients. CONCLUSIONS: When medical care provided to DNR patients is clearly indicated, healthcare professionals will provide the medical care determined by patient/surrogate decision-makers and healthcare professionals, rather than blindly decreasing medical care. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12916-014-0146-x) contains supplementary material, which is available to authorized users. BioMed Central 2014-08-29 /pmc/articles/PMC4156651/ /pubmed/25175307 http://dx.doi.org/10.1186/s12916-014-0146-x Text en © Chen et al.; licensee BioMed Central Ltd. 2014 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Chen, Yen-Yuan
Gordon, Nahida H
Connors, Alfred F
Garland, Allan
Chang, Shan-Chwen
Youngner, Stuart J
Two distinct Do-Not-Resuscitate protocols leaving less to the imagination: an observational study using propensity score matching
title Two distinct Do-Not-Resuscitate protocols leaving less to the imagination: an observational study using propensity score matching
title_full Two distinct Do-Not-Resuscitate protocols leaving less to the imagination: an observational study using propensity score matching
title_fullStr Two distinct Do-Not-Resuscitate protocols leaving less to the imagination: an observational study using propensity score matching
title_full_unstemmed Two distinct Do-Not-Resuscitate protocols leaving less to the imagination: an observational study using propensity score matching
title_short Two distinct Do-Not-Resuscitate protocols leaving less to the imagination: an observational study using propensity score matching
title_sort two distinct do-not-resuscitate protocols leaving less to the imagination: an observational study using propensity score matching
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156651/
https://www.ncbi.nlm.nih.gov/pubmed/25175307
http://dx.doi.org/10.1186/s12916-014-0146-x
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