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Mesenchymal stem cells exert anti-proliferative effect on lipopolysaccharide-stimulated BV2 microglia by reducing tumour necrosis factor-α levels
BACKGROUND: Progression of neurodegenerative diseases occurs when microglia, upon persistent activation, perpetuate a cycle of damage in the central nervous system. Use of mesenchymal stem cells (MSC) has been suggested as an approach to manage microglia activation based on their immunomodulatory fu...
Autores principales: | Jose, Shinsmon, Tan, Shi Wei, Ooi, Yin Yin, Ramasamy, Rajesh, Vidyadaran, Sharmili |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156657/ https://www.ncbi.nlm.nih.gov/pubmed/25182840 http://dx.doi.org/10.1186/s12974-014-0149-8 |
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