Cargando…
Characterization and optimization of heroin hapten-BSA conjugates: method development for the synthesis of reproducible hapten-based vaccines
A potential new treatment for drug addiction is immunization with vaccines that induce antibodies that can abrogate the addictive effects of the drug of abuse. One of the challenges in the development of a vaccine against drugs of abuse is the availability of an optimum procedure that gives reproduc...
Autores principales: | Torres, Oscar B., Jalah, Rashmi, Rice, Kenner C., Li, Fuying, Antoline, Joshua F. G., Iyer, Malliga R., Jacobson, Arthur E., Boutaghou, Mohamed Nazim, Alving, Carl R., Matyas, Gary R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156789/ https://www.ncbi.nlm.nih.gov/pubmed/25084736 http://dx.doi.org/10.1007/s00216-014-8035-x |
Ejemplares similares
-
A simple nonradioactive method for the determination of the binding affinities of antibodies induced by hapten bioconjugates for drugs of abuse
por: Torres, Oscar B., et al.
Publicado: (2015) -
A rapid solution-based method for determining the affinity of heroin hapten-induced antibodies to heroin, its metabolites, and other opioids
por: Torres, Oscar B., et al.
Publicado: (2018) -
A Stable Heroin
Analogue That Can Serve as a Vaccine
Hapten to Induce Antibodies That Block the Effects of Heroin and Its
Metabolites in Rodents and That Cross-React Immunologically with Related
Drugs of Abuse
por: Sulima, Agnieszka, et al.
Publicado: (2017) -
Heroin-HIV-1 (H2) vaccine: induction of dual immunologic effects with a heroin hapten-conjugate and an HIV-1 envelope V2 peptide with liposomal lipid A as an adjuvant
por: Torres, Oscar B., et al.
Publicado: (2017) -
Design, Synthesis, and In Vivo Evaluation of C1-Linked 4,5-Epoxymorphinan Haptens for Heroin Vaccines
por: Sulima, Agnieszka, et al.
Publicado: (2022)