Cargando…

Synthesis and Anticonvulsant Evaluation of some New 6-(Substituted-phenyl)thiazolo[3,2-b][1,2,4]triazole Derivatives in Mice

Epilepsy is the most frequent nearological affiction and afflicts 1% about of the world’s population. Currently there is an urgent need for the development of novel anticonvulsants with higher levels of potency and lower levels of toxicity. In this paper, a series of new 6-(substituted-phenyl)thiazo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Deng, Xian-Qing, Song, Ming-Xia, Gong, Guo-Hua, Wang, Shi-Ben, Quan, Zhe-Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shaheed Beheshti University of Medical Sciences 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157021/ https://www.ncbi.nlm.nih.gov/pubmed/25237341

Ejemplares similares

Synthesis of Novel 7-Substituted-5-phenyl-[1,2,4]triazolo[1,5-a] Pyrimidines with Anticonvulsant Activity
por: Jiang, Nan, et al.
Publicado: (2012)

Synthesis and Anticonvulsant Activity Evaluation of 3-alkoxy-4-(4-(hexyloxy/heptyloxy)phenyl)-4H-1,2,4 -triazole
por: Fang, Ying-Quan, et al.
Publicado: (2015)

7-Chloro-3-phenylbenzo[4,5]thiazolo[2,3-c][1,2,4]triazole
por: Fun, Hoong-Kun, et al.
Publicado: (2011)

Design and synthesis of some substituted thiazolo[3,2-a]pyrimidine derivatives of potential biological activities
por: Abdel Moty, Samia G., et al.
Publicado: (2016)

Synthesis, Characterization and In Vitro Evaluation of Novel 5-Ene-thiazolo[3,2-b][1,2,4]triazole-6(5H)-ones as Possible Anticancer Agents
por: Holota, Serhii, et al.
Publicado: (2021)

Regioselectivity of the alkylation of S-substituted 1,2,4-triazoles with dihaloalkanes
por: Boraei, Ahmed T. A., et al.
Publicado: (2016)

Synthesis, Characterization, and Biological Evaluation of Novel 7-Oxo-7H-thiazolo[3,2-b]-1,2,4-triazine-2-carboxylic Acid Derivatives
por: Cai, Dong, et al.
Publicado: (2020)

Recent developments on triazole nucleus in anticonvulsant compounds: a review
por: Song, Ming-Xia, et al.
Publicado: (2018)

3-Phenyl-1H-1,2,4-triazol-5-amine–5-phenyl-1H-1,2,4-triazol-3-amine (1/1)
por: Dolzhenko, Anton V., et al.
Publicado: (2008)

Novel Strategy for Non-Aqueous Bioconjugation of Substituted Phenyl-1,2,4-triazole-3,5-dione Analogues
por: Hiscocks, Hugh G., et al.
Publicado: (2022)

Synthesis of 3(2)-phosphonylated thiazolo[3,2-a]oxopyrimidines
por: Kaskevich, Ksenia I, et al.
Publicado: (2020)

Synthesis of 5-Alkoxythieno[2,3-e][1,2,4]triazolo[4,3-c]pyrimidine Derivatives and Evaluation of Their Anticonvulsant Activities
por: Wang, Shi-Ben, et al.
Publicado: (2015)

Thermal Rearrangement of Allyl Substituted Unsymmetric 4H-1,2,4-Triazoles to the Corresponding 1H-1,2,4-triazoles.
por: Jørgensen, Kåre B., et al.
Publicado: (2001)

Studies on the Anticonvulsant Activity and Influence on GABA-ergic Neurotransmission of 1,2,4-Triazole-3-thione-Based Compounds
por: Plech, Tomasz, et al.
Publicado: (2014)

Synthesis of Benzo[4,5]thiazolo[2,3-c][1,2,4]triazole Derivatives via C-H Bond Functionalization of Disulfide Intermediates
por: Ardón-Muñoz, Luis G., et al.
Publicado: (2022)

2-[(3-Aminoalkyl-(alkaryl-,aryl-))-(1)H-1,2,4-triazol-5-yl]anilines: synthesis and anticonvulsant activity
por: MARTYNENKO, Yulya, et al.
Publicado: (2020)

Synthesis and Pharmacological Activities of Some New 3-Substituted-4-Amino-5-Mercapto-1,2,4-Triazoles
por: Desai, Shobha R., et al.
Publicado: (2011)

Synthesis, Characterization and Antibacterial Activity of some Novel Thiosemicarbazides, 1,2,4-Triazol-3-thiols and their S-substituted Derivatives
por: Kalhor, Mehdi, et al.
Publicado: (2015)

1,2,4-Triazole-based anticonvulsant agents with additional ROS scavenging activity are effective in a model of pharmacoresistant epilepsy
por: Kaproń, Barbara, et al.
Publicado: (2020)

Synthesis and Evaluation of the Anticonvulsant Activities of 4-(2-(Alkylthio)benzo[d]oxazol-5-yl)-2,4-dihydro-3H-1,2,4-triazol-3-ones
por: Song, Ming-Xia, et al.
Publicado: (2018)

1-Phenyl-2-(1H-1,2,4-triazol-1-yl)ethanone
por: Özel Güven, Özden, et al.
Publicado: (2008)

1-Phenyl-2-(1H-1,2,4-triazol-1-yl)ethanol
por: Özel Güven, Özden, et al.
Publicado: (2008)

Synthesis of Two Novel 3-Amino-5-[4-chloro-2-phenoxyphenyl]-4H-1,2,4-triazoles with Anticonvulsant Activity
por: Mahdavi, Mohammad, et al.
Publicado: (2010)

3-(2-Bromophenyl)thiazolo[3,2-a]benzimidazole
por: Wang, Zhi-Ming, et al.
Publicado: (2011)

Crystal structure of (2-methyl-4-phenyl-4H-benzo[4,5]thiazolo[3,2-a]pyrimidin-3-yl)(phenyl)methanone
por: Sankar, T., et al.
Publicado: (2015)

Synthesis and Antimicrobial Activities of Some New 1,2,4-Triazole Derivatives
por: Bektaş, Hakan, et al.
Publicado: (2010)

Facile Synthesis of 3-Substituted Thiazolo[2,3-α]tetrahydroisoquinolines
por: Huang, Sheng-Han, et al.
Publicado: (2021)

New Substituted 5-Benzylideno-2-Adamantylthiazol[3,2-b][1,2,4]Triazol-6(5H)ones as Possible Anti-Inflammatory Agents
por: Tratrat, Christophe, et al.
Publicado: (2021)

5-Amino-3-methyl-1-phenyl-1H-1,2,4-triazole
por: Allouch, Fatma, et al.
Publicado: (2008)

Substitution of anticonvulsant drugs
por: Steinhoff, Bernhard J, et al.
Publicado: (2009)

1-[2-(2,4-Dichlorophenyl)pentyl]-1H-1,2,4-triazole
por: Rizzoli, Corrado, et al.
Publicado: (2009)

Thiazolo[3,2-a]benzimidazoles: Synthetic Strategies, Chemical Transformations and Biological Activities
por: Al-Rashood, Khalid A., et al.
Publicado: (2010)

4-(3-Methylphenyl)-3-phenyl-5-(2-pyridyl)-4H-1,2,4-triazole
por: Gong, Xiaoning, et al.
Publicado: (2009)

Synthesis, Antibacterial and Antitubercular Activities of Some 5H-Thiazolo[3,2-a]pyrimidin-5-ones and Sulfonic Acid Derivatives
por: Cai, Dong, et al.
Publicado: (2015)

Synthesis, Antibacterial and Antifungal Activity of 4-Substituted-5-Aryl-1,2,4-Triazoles
por: Colanceska-Ragenovic, Katica, et al.
Publicado: (2001)

Bis(5-phenyl-1H-1,2,4-triazol-3-yl) disulfide dihydrate
por: Zhu, Ai-Xin, et al.
Publicado: (2011)

Teicoplanin-Modified HPLC Column as a Source of Experimental Parameters for Prediction of the Anticonvulsant Activity of 1,2,4-Triazole-3-Thiones by the Regression Models
por: Flieger, Jolanta, et al.
Publicado: (2020)

Effect of Linker Elongation on the VGSC Affinity and Anticonvulsant Activity among 4-Alkyl-5-aryl-1,2,4-triazole-3-thione Derivatives
por: Paruch, Kinga, et al.
Publicado: (2023)

1-[2-(4-Bromobenzyloxy)-2-phenylethyl]-1H-1,2,4-triazole
por: Özel Güven, Özden, et al.
Publicado: (2008)

3-[(4-Phenoxyphenyl)sulfanyl]-5-phenyl-1H-1,2,4-triazole
por: Ben Othman, Raja, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ftjjmm34d068ip3peei9lmcop4