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Embryonic cerebrospinal fluid in brain development: neural progenitor control

Due to the effort of several research teams across the world, today we have a solid base of knowledge on the liquid contained in the brain cavities, its composition, and biological roles. Although the cerebrospinal fluid (CSF) is among the most relevant parts of the central nervous system from the p...

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Autores principales: Gato, Angel, Alonso, M. Isabel, Martín, Cristina, Carnicero, Estela, Moro, José Antonio, De la Mano, Aníbal, Fernández, José M. F., Lamus, Francisco, Desmond, Mary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Croatian Medical Schools 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157377/
https://www.ncbi.nlm.nih.gov/pubmed/25165044
http://dx.doi.org/10.3325/cmj.2014.55.299
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author Gato, Angel
Alonso, M. Isabel
Martín, Cristina
Carnicero, Estela
Moro, José Antonio
De la Mano, Aníbal
Fernández, José M. F.
Lamus, Francisco
Desmond, Mary E.
author_facet Gato, Angel
Alonso, M. Isabel
Martín, Cristina
Carnicero, Estela
Moro, José Antonio
De la Mano, Aníbal
Fernández, José M. F.
Lamus, Francisco
Desmond, Mary E.
author_sort Gato, Angel
collection PubMed
description Due to the effort of several research teams across the world, today we have a solid base of knowledge on the liquid contained in the brain cavities, its composition, and biological roles. Although the cerebrospinal fluid (CSF) is among the most relevant parts of the central nervous system from the physiological point of view, it seems that it is not a permanent and stable entity because its composition and biological properties evolve across life. So, we can talk about different CSFs during the vertebrate life span. In this review, we focus on the CSF in an interesting period, early in vertebrate development before the formation of the choroid plexus. This specific entity is called “embryonic CSF.” Based on the structure of the compartment, CSF composition, origin and circulation, and its interaction with neuroepithelial precursor cells (the target cells) we can conclude that embryonic CSF is different from the CSF in later developmental stages and from the adult CSF. This article presents arguments that support the singularity of the embryonic CSF, mainly focusing on its influence on neural precursor behavior during development and in adult life.
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spelling pubmed-41573772014-09-08 Embryonic cerebrospinal fluid in brain development: neural progenitor control Gato, Angel Alonso, M. Isabel Martín, Cristina Carnicero, Estela Moro, José Antonio De la Mano, Aníbal Fernández, José M. F. Lamus, Francisco Desmond, Mary E. Croat Med J Cerebrospinal Fluid Physiology and Movement Due to the effort of several research teams across the world, today we have a solid base of knowledge on the liquid contained in the brain cavities, its composition, and biological roles. Although the cerebrospinal fluid (CSF) is among the most relevant parts of the central nervous system from the physiological point of view, it seems that it is not a permanent and stable entity because its composition and biological properties evolve across life. So, we can talk about different CSFs during the vertebrate life span. In this review, we focus on the CSF in an interesting period, early in vertebrate development before the formation of the choroid plexus. This specific entity is called “embryonic CSF.” Based on the structure of the compartment, CSF composition, origin and circulation, and its interaction with neuroepithelial precursor cells (the target cells) we can conclude that embryonic CSF is different from the CSF in later developmental stages and from the adult CSF. This article presents arguments that support the singularity of the embryonic CSF, mainly focusing on its influence on neural precursor behavior during development and in adult life. Croatian Medical Schools 2014-08 /pmc/articles/PMC4157377/ /pubmed/25165044 http://dx.doi.org/10.3325/cmj.2014.55.299 Text en Copyright © 2014 by the Croatian Medical Journal. All rights reserved. http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Cerebrospinal Fluid Physiology and Movement
Gato, Angel
Alonso, M. Isabel
Martín, Cristina
Carnicero, Estela
Moro, José Antonio
De la Mano, Aníbal
Fernández, José M. F.
Lamus, Francisco
Desmond, Mary E.
Embryonic cerebrospinal fluid in brain development: neural progenitor control
title Embryonic cerebrospinal fluid in brain development: neural progenitor control
title_full Embryonic cerebrospinal fluid in brain development: neural progenitor control
title_fullStr Embryonic cerebrospinal fluid in brain development: neural progenitor control
title_full_unstemmed Embryonic cerebrospinal fluid in brain development: neural progenitor control
title_short Embryonic cerebrospinal fluid in brain development: neural progenitor control
title_sort embryonic cerebrospinal fluid in brain development: neural progenitor control
topic Cerebrospinal Fluid Physiology and Movement
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157377/
https://www.ncbi.nlm.nih.gov/pubmed/25165044
http://dx.doi.org/10.3325/cmj.2014.55.299
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