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Deformable elastic network refinement for low-resolution macromolecular crystallography
Crystals of membrane proteins and protein complexes often diffract to low resolution owing to their intrinsic molecular flexibility, heterogeneity or the mosaic spread of micro-domains. At low resolution, the building and refinement of atomic models is a more challenging task. The deformable elastic...
Autores principales: | Schröder, Gunnar F., Levitt, Michael, Brunger, Axel T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157441/ https://www.ncbi.nlm.nih.gov/pubmed/25195739 http://dx.doi.org/10.1107/S1399004714016496 |
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