Cargando…
Rac1 at the crossroad of actin dynamics and neuroinflammation in Amyotrophic Lateral Sclerosis
Rac1 is a major player of the Rho family of small GTPases that controls multiple cell signaling pathways, such as the organization of cytoskeleton (including adhesion and motility), cell proliferation, apoptosis and activation of immune cells. In the nervous system, in particular, Rac1 GTPase plays...
Autores principales: | D’Ambrosi, Nadia, Rossi, Simona, Gerbino, Valeria, Cozzolino, Mauro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157560/ https://www.ncbi.nlm.nih.gov/pubmed/25249940 http://dx.doi.org/10.3389/fncel.2014.00279 |
Ejemplares similares
-
Mitochondrial dynamism and the pathogenesis of Amyotrophic Lateral Sclerosis
por: Cozzolino, Mauro, et al.
Publicado: (2015) -
Targeting S100A4 with niclosamide attenuates inflammatory and profibrotic pathways in models of amyotrophic lateral sclerosis
por: Milani, Martina, et al.
Publicado: (2021) -
Fibrosis as a common trait in amyotrophic lateral sclerosis tissues
por: Apolloni, Savina, et al.
Publicado: (2021) -
Dysregulated microRNAs in amyotrophic lateral sclerosis microglia modulate genes linked to neuroinflammation
por: Parisi, C, et al.
Publicado: (2013) -
The S100A4 Transcriptional Inhibitor Niclosamide Reduces Pro-Inflammatory and Migratory Phenotypes of Microglia: Implications for Amyotrophic Lateral Sclerosis
por: Serrano, Alessia, et al.
Publicado: (2019)