Lysine Acetylation Controls Local Protein Conformation by Influencing Proline Isomerization

Gene transcription responds to stress and metabolic signals to optimize growth and survival. Histone H3 (H3) lysine 4 trimethylation (K4me3) facilitates state changes, but how levels are coordinated with the environment is unclear. Here, we show that isomerization of H3 at the alanine 15-proline 16...

Descripción completa

Detalles Bibliográficos
Autores principales: Howe, Françoise S., Boubriak, Ivan, Sale, Matthew J., Nair, Anitha, Clynes, David, Grijzenhout, Anne, Murray, Struan C., Woloszczuk, Ronja, Mellor, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157579/
https://www.ncbi.nlm.nih.gov/pubmed/25127513
http://dx.doi.org/10.1016/j.molcel.2014.07.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157579/
https://www.ncbi.nlm.nih.gov/pubmed/25127513
http://dx.doi.org/10.1016/j.molcel.2014.07.004

Ejemplares similares