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Experimental virotherapy of chemoresistant pancreatic carcinoma using infectivity-enhanced fiber-mosaic oncolytic adenovirus

Pancreatic cancer is a significant clinical problem and novel therapeutic approaches are desperately needed. Recent advances in conditionally replicative adenovirus-based (CRAd) oncolytic virus design allow the application of CRAd vectors as a therapeutic strategy to efficiently target and eradicate...

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Detalles Bibliográficos
Autores principales: Kaliberov, Sergey A., Kaliberova, Lyudmila N., Buchsbaum, Donald J., Curiel, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157623/
https://www.ncbi.nlm.nih.gov/pubmed/24903014
http://dx.doi.org/10.1038/cgt.2014.26