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Genome-Wide Binding and Transcriptome Analysis of Human Farnesoid X Receptor in Primary Human Hepatocytes

BACKGROUND & AIMS: Farnesoid X receptor (FXR, NR1H4) is a ligand-activated transcription factor, belonging to the nuclear receptor superfamily. FXR is highly expressed in the liver and is essential in regulating bile acid homeostasis. FXR deficiency is implicated in numerous liver diseases and m...

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Detalles Bibliográficos
Autores principales:	Zhan, Le, Liu, Hui-Xin, Fang, Yaping, Kong, Bo, He, Yuqi, Zhong, Xiao-bo, Fang, Jianwen, Wan, Yu-Jui Yvonne, Guo, Grace L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157742/ https://www.ncbi.nlm.nih.gov/pubmed/25198545 http://dx.doi.org/10.1371/journal.pone.0105930

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